{"id":624,"date":"2014-03-24T08:36:37","date_gmt":"2014-03-24T13:36:37","guid":{"rendered":"http:\/\/www.prostateblog.com\/?p=624"},"modified":"2014-10-28T19:03:13","modified_gmt":"2014-10-29T00:03:13","slug":"prostate-cancer-treatment-comparisons","status":"publish","type":"post","link":"http:\/\/www.prostateblog.com\/?p=624","title":{"rendered":"Prostate Cancer Treatment Comparisons"},"content":{"rendered":"

This just in from the UF Proton Therapy Institute – I’ve coped their table below. As they state:<\/p>\n

“Part of the decision-making process is to learn each treatment\u2019s potential for cure (disease control) and for maintaining a good quality of life after treatment. The following table shows the most current prostate cancer patient outcomes data available for both proton therapy and surgery.”<\/p>\n

Thanks to my old flight instructor “Doc” Harkins for passing this along…….<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Decision Points<\/strong><\/td>\nProton Therapy for Prostate Cancer<\/strong><\/td>\nSurgery for Prostate Cancer<\/strong><\/td>\n<\/tr>\n
Disease Control<\/strong>*<\/sup><\/td>\n99%-76%1<\/sup><\/td>\n84%-60%2,3<\/sup><\/td>\n<\/tr>\n
Treatment<\/strong><\/td>\n<\/tr>\n
Major complication rate<\/td>\n1%1**<\/sup><\/td>\n28.6%4<\/sup><\/td>\n<\/tr>\n
Invasive Procedure<\/td>\nNo<\/td>\nYes<\/td>\n<\/tr>\n
Long Recovery Time<\/td>\nNo<\/td>\nYes<\/td>\n<\/tr>\n
Fatigue<\/td>\nNo<\/td>\nYes<\/td>\n<\/tr>\n
30-day mortality rate<\/td>\n0%<\/td>\n0.5%4<\/sup><\/td>\n<\/tr>\n
Rehospitalization rate<\/td>\n0% (N\/A)<\/td>\n4.5%4<\/sup><\/td>\n<\/tr>\n
Side Effects<\/strong>
\nPercent of patients who experience a change post treatment<\/td>\n<\/tr>\n
Incontinence<\/td>\n0%1<\/sup><\/td>\n6%-30%4<\/sup><\/td>\n<\/tr>\n
Impotence<\/td>\n34%1<\/sup><\/td>\n60%-80%1<\/sup><\/td>\n<\/tr>\n
Inguinal hernia<\/td>\n0% (N\/A)<\/td>\n7%-21%4<\/sup><\/td>\n<\/tr>\n
Fecal Incontinence<\/td>\n1.4%1<\/sup><\/td>\n17%-32%5<\/sup><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

*Disease control is defined as freedom from clinical or PSA progression at five years.<\/p>\n

**1% per Common Terminology Criteria for Adverse Events (CTCAE) v4.0; 5.3% per CTCAE v3.0<\/p>\n

1.Mendenhall, NP et al. Five-Year Outcomes from 3 Prospective Trials of Image-Guided Proton Therapy for Prostate Cancer. Int J Radiation Oncol Biol Phys 2014 March; 88(3):596-602.<\/p>\n

2.Han, M et al. Long-Term Biochemical Disease-Free and Cancer-Specific Survival Following Anatomic Radical Retropubic Prostatectomy: The 15-Year Johns Hopkins Experience. Urol Clin North Am 2001 Aug; 28(3):555-65.<\/p>\n

3.Qi, P et al. Long-Term Oncological Outcomes of Men Undergoing Radical Prostatectomy With Preoperative Prostate-Specific Antigen <2.5 ng\/ml and 2.5-4 ng\/ml. Urol Oncol 2013 Nov; 31(8):1527-32.<\/p>\n

4.Treatment Option Overview for Prostate Cancer, Health Professional Version<\/a>. Retrieved Aug. 28, 2013.<\/p>\n

5.Bishoff JT et al. Incidence of fecal and urinary incontinence following radical perineal and retropubic prostatectomy in a national population. J Urol 160 (2): 454-8, 1998.<\/p>\n

3.7.14 Reviewed by Nancy P. Mendenhall, M.D.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

This just in from the UF Proton Therapy Institute – I’ve coped their table below. As they state: “Part of the decision-making process is to learn each treatment\u2019s potential for cure (disease control) and for maintaining a good quality of life after treatment. The following table shows the most current prostate cancer patient outcomes data […]<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_s2mail":"yes","footnotes":""},"categories":[1],"tags":[],"class_list":["post-624","post","type-post","status-publish","format-standard","hentry","category-general"],"aioseo_notices":[],"_links":{"self":[{"href":"http:\/\/www.prostateblog.com\/index.php?rest_route=\/wp\/v2\/posts\/624"}],"collection":[{"href":"http:\/\/www.prostateblog.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.prostateblog.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.prostateblog.com\/index.php?rest_route=\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"http:\/\/www.prostateblog.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=624"}],"version-history":[{"count":3,"href":"http:\/\/www.prostateblog.com\/index.php?rest_route=\/wp\/v2\/posts\/624\/revisions"}],"predecessor-version":[{"id":672,"href":"http:\/\/www.prostateblog.com\/index.php?rest_route=\/wp\/v2\/posts\/624\/revisions\/672"}],"wp:attachment":[{"href":"http:\/\/www.prostateblog.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=624"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.prostateblog.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=624"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.prostateblog.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=624"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}